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Ligand · ZJP

ZJP · Cyclopentyl {(2r,4s,6s,12z,13as,14ar,16as)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14A-[(1-methylcyclopropane-1-sulfonyl)carbamoyl]-5,16-dioxo-1, 2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-hexadecahydrocyclopropa[e]pyrrolo[1,2-A][1, 4]diazacyclopentadecin-6-yl}carbamate

ZJP, Cyclopentyl {(2r,4s,6s,12z,13as,14ar,16as)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14A-[(1-methylcyclopropane-1-sulfonyl)carbamoyl]-5,16-dioxo-1, 2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-hexadecahydrocyclopropa[e]pyrrolo[1,2-A][1…

Component
ZJP
Formula
C38 H50 N6 O9 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

ZJP in 2 structures; the first of them:

  • 7MMD · Crystal structure of HCV NS3/4A D168A protease in complex with JZ01-19 · ZJP A1206 · binds GLN1041, THR1042, PHE1043, TYR1056, HIS1057, GLY1058, VAL1078, ASP1081 and 13 more
  • 7MMD · Crystal structure of HCV NS3/4A D168A protease in complex with JZ01-19 · ZJP A1206 · binds GLN1041, THR1042, PHE1043, TYR1056, HIS1057, GLY1058, VAL1078, ASP1081 and 13 more

Residues it binds most

ALA 2, ARG 2, GLY 2, PHE 2, SER 2, VAL 2, ASP 2, GLN 2, HIS 2, ILE 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • SO4 · Sulfate ion
  • EDO · 1,2-ethanediol

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