ZJG · Cyclobutyl {(2r,4s,6s,12z,13as,14ar,16as)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14A-[(1-methylcyclopropane-1-sulfonyl)carbamoyl]-5,16-dioxo-1, 2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-hexadecahydrocyclopropa[e]pyrrolo[1,2-A][1, 4]diazacyclopentadecin-6-yl}carbamate

Binding sites

ZJG in 4 structures; the first of them:

• 7MM3 · Crystal structure of HCV NS3/4A protease in complex with NR01-127 · ZJG A1202 · binds GLN1041, THR1042, PHE1043, TYR1056, HIS1057, GLY1058, VAL1078, ASP1081 and 12 more
• 7MMB · Crystal structure of HCV NS3/4A D168A protease in complex with NR01-127 · ZJG A1201 · binds GLN1041, THR1042, PHE1043, TYR1056, HIS1057, GLY1058, VAL1078, ASP1081 and 11 more
• 7MM3 · Crystal structure of HCV NS3/4A protease in complex with NR01-127 · ZJG A1202 · binds GLN1041, THR1042, PHE1043, TYR1056, HIS1057, GLY1058, VAL1078, ASP1081 and 11 more
• 7MMB · Crystal structure of HCV NS3/4A D168A protease in complex with NR01- 127 · ZJG A1201 · binds GLN1041, THR1042, PHE1043, TYR1056, HIS1057, GLY1058, VAL1078, ASP1081 and 11 more

Residues it binds most

ALA 4, GLY 4, PHE 4, SER 4, ARG 4, ASP 4, VAL 4, GLN 4, HIS 4, ILE 4 (residue and the binding sites it lines).

Found with

• ZN · Zinc ion
• SO4 · Sulfate ion
• EDO · 1,2-ethanediol