GL1X · GenesisL1 explorer

Ligand · ZG7

ZG7 · (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl) cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile

ZG7, (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl) cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile (C22 H14 Br Cl N4 O2, 481.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding…

Component
ZG7
Formula
C22 H14 Br Cl N4 O2
Class
ligand
Structures
2
PDB entries
2

Binding sites

ZG7 in 2 structures; the first of them:

  • 7MI3 · Signal subtracted reconstruction of AAA2, AAA3, and AAA4 domains of dynein in the… · ZG7 A4201 · binds VAL2730, PRO2731, MET2732, VAL2733, HIS2735, ALA2761, SER2762, ARG2763 and 8 more
  • 7MI6 · Yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone- based compound… · ZG7 A4201 · binds VAL2391, ILE2392, THR2397, PRO2420, GLY2421, SER2422, GLY2423, LYS2424 and 8 more

Residues it binds most

THR 4, ILE 4, ARG 4, GLY 4, PRO 4, VAL 4, LYS 4, MET 4, SER 4, ALA 2 (residue and the binding sites it lines).

Found with

  • ATP · Adenosine-5'-triphosphate
  • MG · Magnesium ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.