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Ligand · ZG2

ZG2 · 5-[5-benzyl-4-(2-oxo-2-pyrrolidin-1-ylethyl)-1,3-oxazol-2-yl]-1-ethyl-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-b]pyridin-4-amine

ZG2, 5-[5-benzyl-4-(2-oxo-2-pyrrolidin-1-ylethyl)-1,3-oxazol-2-yl]-1-ethyl-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-b]pyridin-4-amine (C29 H34 N6 O3, 514.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
ZG2
Formula
C29 H34 N6 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

ZG2 in 2 structures; the first of them:

  • 3O57 · Catalytic domain of human phosphodiesterase 4b2b in complex with a 5-heterocycle… · ZG2 A506 · binds TYR233, HIS234, SER282, THR345, MET347, ASP392, LEU393, ASN395 and 12 more
  • 3O57 · Catalytic domain of human phosphodiesterase 4B2B in complex with a 5- heterocycle… · ZG2 A506 · binds TYR233, HIS234, SER282, THR345, MET347, ASP392, LEU393, ASN395 and 12 more

Residues it binds most

TYR 2, MET 2, PHE 2, SER 2, THR 2, ASN 2, ASP 2, GLN 2, GLY 2, HIS 2 (residue and the binding sites it lines).

Found with

  • ARS · Arsenic
  • MG · Magnesium ion
  • ZN · Zinc ion
  • GOL · Glycerol

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