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Ligand · ZG1

ZG1 · 1-ethyl-5-[3-(2-oxo-2-pyrrolidin-1-ylethyl)-1,2,4-oxadiazol-5-yl]-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-b]pyridin-4-amine

ZG1, 1-ethyl-5-[3-(2-oxo-2-pyrrolidin-1-ylethyl)-1,2,4-oxadiazol-5-yl]-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-b]pyridin-4-amine (C21 H27 N7 O3, 425.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component
ZG1
Formula
C21 H27 N7 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

ZG1 in 2 structures; the first of them:

  • 3O56 · Catalytic domain of human phosphodiesterase 4b2b in complex with a 5-heterocycle… · ZG1 A506 · binds TYR233, HIS234, SER282, MET347, ASP392, LEU393, ASN395, PRO396 and 8 more
  • 3O56 · Catalytic domain of human phosphodiesterase 4B2B in complex with a 5- heterocycle… · ZG1 A506 · binds TYR233, HIS234, SER282, MET347, ASP392, LEU393, ASN395, PRO396 and 8 more

Residues it binds most

MET 2, PHE 2, TYR 2, ASN 2, ASP 2, GLN 2, HIS 2, ILE 2, LEU 2, PRO 2 (residue and the binding sites it lines).

Found with

  • ARS · Arsenic
  • MG · Magnesium ion
  • ZN · Zinc ion
  • GOL · Glycerol

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