Ligand · ZAR
ZAR · 6-(4-difluoromethoxy-3-methoxy-phenyl)-2H-pyridazin-3-one
ZAR, 6-(4-difluoromethoxy-3-methoxy-phenyl)-2H-pyridazin-3-one (C12 H10 F2 N2 O3, 268.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it…
- Component
- ZAR
- Formula
- C12 H10 F2 N2 O3
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
ZAR in 4 structures; the first of them:
- 1MKD · crystal structure of PDE4D catalytic domain and zardaverine complex · ZAR A3001 · binds TYR256, MET370, ASN418, PRO419, TYR426, TRP429, THR430, ILE433 and 5 more
- 1XOR · Catalytic Domain Of Human Phosphodiesterase 4D In Complex With Zardaverine · ZAR A701 · binds TYR159, HIS160, HIS164, HIS200, ASP201, ASP318, LEU319, ASN321 and 9 more
- 1MKD · Crystal structure of PDE4D catalytic domain and zardaverine complex · ZAR A3001 · binds TYR256, MET370, ASN418, PRO419, TYR426, TRP429, THR430, ILE433 and 5 more
- 1XOR · Catalytic domain of human phosphodiesterase 4D in complex with zardaverine · ZAR A701 · binds TYR159, HIS160, HIS164, HIS200, ASP201, ASP318, LEU319, ASN321 and 9 more
Residues it binds most
PHE 28, MET 28, TYR 28, ASN 28, GLN 28, ILE 28, SER 28, THR 28, TRP 28, PRO 24 (residue and the binding sites it lines).
Found with
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