GL1X · GenesisL1 explorer

Ligand · Z8Z

Z8Z · N~2~-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-N-[(2R,5R)-5-{[(1,3-oxazol-5-ylmethoxy)carbonyl]amino}-1,6-diphenylhexan-2-yl]-L-valinamide

Z8Z, N~2~-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-N-[(2R,5R)-5-{[(1,3-oxazol-5-ylmethoxy)carbonyl]amino}-1,6-diphenylhexan-2-yl]-L-valinamide (C37 H48 N6 O5 S, 688.9 g/mol), in the MolNFT structures on GenesisL1: bound…

Component
Z8Z
Formula
C37 H48 N6 O5 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

Z8Z in 2 structures; the first of them:

  • 4I4G · Crystal structure of CYP3A4 ligated to oxazole-substituted desoxyritonavir · Z8Z A602 · binds TYR53, PHE57, ASP76, ARG105, ARG106, PHE108, MET114, SER119 and 15 more
  • 4I4G · Crystal structure of CYP3A4 ligated to oxazole-substituted desoxyritonavir · Z8Z A602 · binds TYR53, PHE57, ASP76, ARG105, ARG106, PHE108, MET114, SER119 and 15 more

Residues it binds most

PHE 2, ARG 2, ILE 2, ALA 2, LEU 2, THR 2, ASP 2, CYS 2, GLU 2, MET 2 (residue and the binding sites it lines).

Found with

  • HEM · Protoporphyrin IX containing Fe

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