GL1X · GenesisL1 explorer

Ligand · Z8G

Z8G · N-[(3r,3as,9bs)-9B-[(4-fluorophenyl)sulfonyl]-7-(1,1,1, 2,3,3,3-heptafluoropropan-2-yl)-2,3,3A,4,5,9B-hexahydro-1H-cyclopenta[a]naphthalen-3-yl]-2-hydroxy-2-methylpropanamide

Z8G, N-[(3r,3as,9bs)-9B-[(4-fluorophenyl)sulfonyl]-7-(1,1,1, 2,3,3,3-heptafluoropropan-2-yl)-2,3,3A,4,5,9B-hexahydro-1H-cyclopenta[a]naphthalen-3-yl]-2-hydroxy-2-methylpropanamide (C26 H25 F8 N O4 S, 599.5 g/mol), in the MolNFT structures…

Component
Z8G
Formula
C26 H25 F8 N O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

Z8G in 2 structures; the first of them:

  • 7KQJ · Crystal structure of rar-related orphan receptor C (nhis-RORGT(244-487)-L6-SRC1(678-692)… · Z8G A4000 · binds GLN286, TRP317, CYS320, HIS323, LEU324, ALA327, VAL361, MET365 and 11 more
  • 7KQJ · Crystal structure of rar-related orphan receptor C (nhis-RORGT(244- 487)-L6-SRC1(678-692)… · Z8G A4000 · binds GLN286, TRP317, CYS320, HIS323, LEU324, ALA327, VAL361, MET365 and 11 more

Residues it binds most

PHE 2, LEU 2, ALA 2, HIS 2, ILE 2, CYS 2, GLN 2, MET 2, TRP 2, TYR 2 (residue and the binding sites it lines).

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