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Ligand · Z72

Z72 · 8-(cyclopentyloxy)-4-[(3,5-dichloropyridin-4-yl)amino]-7-methoxy-2H-chromen-2-one

Z72, 8-(cyclopentyloxy)-4-[(3,5-dichloropyridin-4-yl)amino]-7-methoxy-2H-chromen-2-one (C20 H18 Cl2 N2 O4, 421.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within…

Component
Z72
Formula
C20 H18 Cl2 N2 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

Z72 in 2 structures; the first of them:

  • 3LY2 · Catalytic Domain of Human Phosphodiesterase 4B in Complex with A Coumarin-Based Inhibitor · Z72 A1000 · binds TYR233, HIS234, THR345, MET347, ASP392, LEU393, ASN395, TYR403 and 9 more
  • 3LY2 · Catalytic domain of human phosphodiesterase 4B in complex with a coumarin-based inhibitor · Z72 A1000 · binds TYR233, HIS234, THR345, MET347, ASP392, LEU393, ASN395, TYR403 and 9 more

Residues it binds most

MET 16, PHE 16, THR 16, TYR 16, ASN 16, ASP 16, GLN 16, HIS 16, ILE 16, LEU 16 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion
  • SO4 · Sulfate ion

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