GL1X · GenesisL1 explorer

Ligand · Z48

Z48 · N-[(1S)-2-hydroxy-1-phenylethyl]-4-[5-methyl-2-(phenylamino)pyrimidin-4-yl]-1H-pyrrole-2-carboxamide

Z48, N-[(1S)-2-hydroxy-1-phenylethyl]-4-[5-methyl-2-(phenylamino)pyrimidin-4-yl]-1H-pyrrole-2-carboxamide (C24 H23 N5 O2, 413.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its…

Component
Z48
Formula
C24 H23 N5 O2
Class
ligand
Structures
4
PDB entries
2

Binding sites

Z48 in 4 structures; the first of them:

  • 3I4B · Crystal structure of GSK3b in complex with a pyrimidylpyrrole inhibitor · Z48 A501 · binds ILE62, ASN64, GLY65, SER66, GLY68, VAL69, VAL70, ALA83 and 15 more
  • 3I5Z · Crystal structure of ERK2 bound to (S)-N-(2-hydroxy-1-phenylethyl)-4-(5-methyl-2-(phenylam… · Z48 A401 · binds ILE29, GLU31, GLY32, ALA33, TYR34, GLY35, MET36, VAL37 and 16 more
  • 3I4B · Crystal structure of GSK3B in complex with a pyrimidylpyrrole inhibitor · Z48 A501 · binds ILE62, ASN64, GLY65, SER66, GLY68, VAL69, VAL70, ALA83 and 15 more
  • 3I5Z · Crystal structure of ERK2 bound to (S)-N-(2-hydroxy-1-phenylethyl)-4… · Z48 A401 · binds ILE29, GLU31, GLY32, ALA33, TYR34, GLY35, MET36, VAL37 and 16 more

Residues it binds most

VAL 6, ASP 6, GLY 6, LEU 6, ASN 6, ILE 6, ALA 6, GLU 6, LYS 6, CYS 6 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.