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Ligand · Z26

Z26 · 2-(5-chloro-2-methoxyphenyl)-N-(isoquinolin-4-yl) acetamide

Z26, 2-(5-chloro-2-methoxyphenyl)-N-(isoquinolin-4-yl) acetamide (C18 H15 Cl N2 O2, 326.8 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it…

Component
Z26
Formula
C18 H15 Cl N2 O2
Class
ligand
Structures
3
PDB entries
2

Binding sites

Z26 in 3 structures; the first of them:

  • 7GFA · Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID… · Z26 A404 · binds HIS41, MET49, PHE140, LEU141, ASN142, SER144, CYS145, HIS163 and 7 more
  • 7S3K · Room temperature X-ray structure of SARS-CoV-2 main protease in complex with compound… · Z26 A401 · binds HIS41, MET49, PHE140, LEU141, ASN142, SER144, CYS145, HIS163 and 7 more
  • 7S3K · Room temperature X-ray structure of SARS-cov-2 main protease in complex with compound… · Z26 A401 · binds HIS41, MET49, PHE140, LEU141, ASN142, SER144, CYS145, HIS163 and 7 more

Residues it binds most

HIS 3, MET 3, ARG 3, ASN 3, ASP 3, CYS 3, GLN 3, GLU 3, LEU 3, PHE 3 (residue and the binding sites it lines).

Found with

  • DMS · Dimethyl sulfoxide

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