GL1X · GenesisL1 explorer

Ligand · YWM

YWM · Diethyl [(4-{(2S,3R)-2-[({[(3r,3as,6ar)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxy-4-[{4-[(1S)-1-hydroxyethyl]benzene-1-sulfonyl}(2-methylpropyl)amino]butyl}phenoxy) methyl]phosphonate

YWM, Diethyl [(4-{(2S,3R)-2-[({[(3r,3as,6ar)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxy-4-[{4-[(1S)-1-hydroxyethyl]benzene-1-sulfonyl}(2-methylpropyl)amino]butyl}phenoxy) methyl]phosphonate (C34 H51 N2 O12 P S, 742.8…

Component
YWM
Formula
C34 H51 N2 O12 P S
Class
ligand
Structures
4
PDB entries
2

Binding sites

YWM in 4 structures; the first of them:

  • 7M9J · HIV-1 Protease WT (NL4-3) in Complex with LR3-68 · YWM A104 · binds LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, ILE47 and 21 more
  • 7M9N · HIV-1 Protease (I84V) in Complex with LR3-68 · YWM A101 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 22 more
  • 7M9J · HIV-1 protease wt (NL4-3) in complex with LR3-68 · YWM A104 · binds LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, ILE47 and 16 more
  • 7M9N · HIV-1 protease (I84V) in complex with LR3-68 · YWM A101 · binds ARG8, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, ILE47 and 20 more

Residues it binds most

GLY 4, ASP 4, VAL 4, ILE 4, LEU 4, ALA 4, PHE 4, PRO 4, ARG 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.