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Ligand · YVQ

YVQ · 3-(1H-indol-3-yl)-6-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazine

YVQ, 3-(1H-indol-3-yl)-6-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazine (C17 H12 N6, 300.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
YVQ
Formula
C17 H12 N6
Class
ligand
Structures
2
PDB entries
1

Binding sites

YVQ in 2 structures; the first of them:

  • 2XEY · Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors · YVQ A1270 · binds LEU15, VAL23, ALA36, LYS38, GLU85, TYR86, CYS87, GLY90 and 4 more
  • 2XEY · Crystal structure of checkpoint kinase 1 (CHK1) in complex with inhibitors · YVQ A1270 · binds LEU15, VAL23, ALA36, LYS38, GLU85, TYR86, CYS87, GLY90 and 4 more

Residues it binds most

GLU 2, LEU 2, ALA 2, ASP 2, CYS 2, GLY 2, LYS 2, SER 2, TYR 2, VAL 2 (residue and the binding sites it lines).

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