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Ligand · YUJ

YUJ · (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(1S)-1-hydroxy-2,3-dihydro-1H-indene-5-sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate

YUJ, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(1S)-1-hydroxy-2,3-dihydro-1H-indene-5-sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate (C30 H40 N2 O8 S, 588.7 g/mol), in the MolNFT structures on…

Component
YUJ
Formula
C30 H40 N2 O8 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

YUJ in 4 structures; the first of them:

  • 7M9S · HIV-1 Protease WT (NL4-3) in Complex with NR01-141 · YUJ A101 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 20 more
  • 7M9V · HIV-1 Protease (I84V) in Complex with NR01-141 · YUJ A101 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 20 more
  • 7M9S · HIV-1 protease wt (NL4-3) in complex with NR01-141 · YUJ A101 · binds ARG8, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, ILE47 and 17 more
  • 7M9V · HIV-1 protease (I84V) in complex with NR01-141 · YUJ A101 · binds ARG8, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, ILE47 and 15 more

Residues it binds most

ASP 4, GLY 4, ILE 4, VAL 4, ALA 4, LEU 4, ARG 4, PRO 4 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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