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Ligand · YRP

YRP · (2R)-N-(4-chlorophenyl)-2-[(1R,3S,5S,6r)-3-(5,6-difluoro-1H-benzimidazol-1-yl)bicyclo[3.1.0]hexan-6-yl]propanamide

YRP, (2R)-N-(4-chlorophenyl)-2-[(1R,3S,5S,6r)-3-(5,6-difluoro-1H-benzimidazol-1-yl)bicyclo[3.1.0]hexan-6-yl]propanamide (C22 H20 Cl F2 N3 O, 415.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
YRP
Formula
C22 H20 Cl F2 N3 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

YRP in 2 structures; the first of them:

  • 7M63 · Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with IACS-70099 · YRP A501 · binds TYR126, CYS129, VAL130, PHE163, PHE164, SER167, VAL170, PHE214 and 12 more
  • 7M63 · Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with iacs-70099 · YRP A501 · binds TYR126, CYS129, VAL130, PHE163, PHE164, SER167, VAL170, PHE214 and 12 more

Residues it binds most

PHE 4, LEU 4, SER 4, VAL 4, ALA 4, ARG 4, CYS 4, GLY 4, HIS 4, ILE 4 (residue and the binding sites it lines).

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