Ligand · YNK

YNK · 7-dimethylphosphoryl-3-[2-[[(3~{S})-6,6-dimethylpiperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1~{H}-indole-6-carbonitrile

YNK, 7-dimethylphosphoryl-3-[2-[[(3~{S})-6,6-dimethylpiperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1~{H}-indole-6-carbonitrile (C23 H26 F3 N6 O P, 490.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB…

Component: YNK
Formula: C23 H26 F3 N6 O P
Class: ligand
Structures: 2
PDB entries: 2

Binding sites

YNK in 2 structures; the first of them:

8R9U · A soakable crystal form of human CDK7 in complex with AMP-PNP · YNK A401 · binds LEU18, GLY19, GLU20, GLY21, PHE23, ALA24, VAL26, ALA39 and 13 more
8S0T · Cryo-EM structure of CAK in complex with SY-5609 · YNK J401 · binds LEU18, GLY19, GLU20, GLY21, ALA24, VAL26, ALA39, LYS41 and 12 more

Residues it binds most

ALA 3, ASP 3, PHE 3, GLU 3, GLY 3, LEU 3, VAL 3, ILE 3, LYS 3, MET 3 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.