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Ligand · YL5

YL5 · [(1R)-2-(3-fluorophenyl)-1-{[6-(4-methylphenyl) thieno[2,3-d]pyrimidin-4-yl]amino}ethyl]phosphonic acid

YL5, [(1R)-2-(3-fluorophenyl)-1-{[6-(4-methylphenyl) thieno[2,3-d]pyrimidin-4-yl]amino}ethyl]phosphonic acid (C21 H19 F N3 O3 P S, 443.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
YL5
Formula
C21 H19 F N3 O3 P S
Class
ligand
Structures
2
PDB entries
1

Binding sites

YL5 in 2 structures; the first of them:

  • 5JV0 · Crystal structure of human FPPS in complex with an allosteric inhibitor CL-08-038 · YL5 F403 · binds ASN59, ARG60, THR63, SER205, PHE206, PHE239, GLN242, LEU246 and 5 more
  • 5JV0 · Crystal structure of human fpps in complex with an allosteric inhibitor cl-08-038 · YL5 F403 · binds ASN59, ARG60, THR63, SER205, PHE206, PHE239, GLN242, LEU246 and 5 more

Residues it binds most

LEU 6, GLU 4, LYS 6, ARG 6, PRO 2, ALA 4, ILE 4, PHE 2, THR 2, TYR 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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