GL1X · GenesisL1 explorer

Ligand · YJA

YJA · 2-[5-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]quinazolin-4-yl]amino]-1H-pyrazol-3-yl]-N-(3-fluorophenyl)ethanamide

YJA, 2-[5-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]quinazolin-4-yl]amino]-1H-pyrazol-3-yl]-N-(3-fluorophenyl)ethanamide (C26 H30 F N7 O3, 507.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
YJA
Formula
C26 H30 F N7 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

YJA in 2 structures; the first of them:

  • 4C2V · Aurora B kinase in complex with the specific inhibitor Barasertib · YJA A1357 · binds ARG97, LEU99, PHE104, VAL107, ALA120, LYS122, LEU124, LEU138 and 16 more
  • 4C2V · Aurora B kinase in complex with the specific inhibitor barasertib · YJA A1357 · binds ARG97, LEU99, PHE104, VAL107, ALA120, LYS122, LEU124, LEU138 and 16 more

Residues it binds most

LEU 4, ALA 4, GLU 4, PHE 4, ARG 4, LYS 4, GLN 4, GLY 4, ILE 4, MET 4 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.