GL1X · GenesisL1 explorer

Ligand · YHY

YHY · N-{3-[4-(dimethylamino)piperidin-1-yl]phenyl}-4-fluoro-7-methyl-1H-indole-2-carboxamide

YHY, N-{3-[4-(dimethylamino)piperidin-1-yl]phenyl}-4-fluoro-7-methyl-1H-indole-2-carboxamide (C23 H27 F N4 O, 394.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
YHY
Formula
C23 H27 F N4 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

YHY in 2 structures; the first of them:

  • 7LZD · Crystal Structure of SETD2 bound to Compound 35 · YHY A1805 · binds TYR1579, VAL1593, TYR1604, TYR1605, PHE1606, MET1607, MET1627, ASN1628 and 8 more
  • 7LZD · Crystal structure of SETD2 bound to compound 35 · YHY A1805 · binds TYR1579, TYR1604, TYR1605, PHE1606, MET1627, HIS1629, PHE1664, TYR1666 and 5 more

Residues it binds most

TYR 2, PHE 2, MET 2, GLU 2, HIS 2, LEU 2, LYS 2, ASN 1, GLN 1, SAM 1 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • DMS · Dimethyl sulfoxide
  • EDO · 1,2-ethanediol
  • SAM · S-adenosylmethionine

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.