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Ligand · YF6

YF6 · N-(1-[1,1-di(pyridin-2-yl)ethyl]-6-{1-methyl-6-oxo-5-[(piperidin-4-yl)amino]-1,6-dihydropyridin-3-yl}-1H-indol-4-yl)ethanesulfonamide

YF6, N-(1-[1,1-di(pyridin-2-yl)ethyl]-6-{1-methyl-6-oxo-5-[(piperidin-4-yl)amino]-1,6-dihydropyridin-3-yl}-1H-indol-4-yl)ethanesulfonamide (C33 H37 N7 O3 S, 611.8 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB…

Component
YF6
Formula
C33 H37 N7 O3 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

YF6 in 4 structures; the first of them:

  • 7JKY · Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with YF3-126 · YF6 A201 · binds TRP81, PRO82, PHE83, GLN85, PRO86, VAL87, ASP88, LYS91 and 9 more
  • 7JKZ · Bromodomain-containing protein 4 (BRD4) bromodomain 2 (BD2) complexed with YF3-126 · YF6 A501 · binds TRP374, PRO375, PHE376, TYR377, LYS378, PRO379, VAL380, ASP381 and 9 more
  • 7JKY · Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with YF3-126 · YF6 A201 · binds TRP81, PRO82, PHE83, GLN85, PRO86, VAL87, ASP88, LYS91 and 5 more
  • 7JKZ · Bromodomain-containing protein 4 (BRD4) bromodomain 2 (BD2) complexed with YF3-126 · YF6 A501 · binds TRP374, PRO375, PHE376, LYS378, PRO379, VAL380, ASP381, LEU385 and 6 more

Residues it binds most

PRO 4, LEU 4, ASP 4, VAL 4, TYR 3, ASN 4, LYS 4, MET 4, PHE 4, TRP 4 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • EDO · 1,2-ethanediol
  • GOL · Glycerol

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