GL1X · GenesisL1 explorer

Ligand · YD7

YD7 · ~{N}-[(5~{R})-2-[2-[(1-methylpyrazol-4-yl) amino]pyrimidin-4-yl]-6,7,8,9-tetrahydro-5~{H}-benzo[7]annulen-5-yl]-3-propan-2-yloxy-azetidine-1-carboxamide

YD7, ~{N}-[(5~{R})-2-[2-[(1-methylpyrazol-4-yl) amino]pyrimidin-4-yl]-6,7,8,9-tetrahydro-5~{H}-benzo[7]annulen-5-yl]-3-propan-2-yloxy-azetidine-1-carboxamide (C26 H33 N7 O2, 475.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2…

Component
YD7
Formula
C26 H33 N7 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

YD7 in 2 structures; the first of them:

  • 7LTY · Bruton's tyrosine kinase in complex with compound 23 · YD7 A701 · binds LEU408, GLY409, THR410, GLY411, GLN412, PHE413, VAL416, ALA428 and 14 more
  • 7LTY · BRUTON'S tyrosine kinase in complex with compound 23 · YD7 A701 · binds LEU408, GLY409, THR410, GLY411, GLN412, PHE413, VAL416, ALA428 and 14 more

Residues it binds most

GLY 2, LEU 2, ALA 2, ASP 2, THR 2, VAL 2, ASN 2, GLN 2, GLU 2, LYS 2 (residue and the binding sites it lines).

Found with

  • DMS · Dimethyl sulfoxide

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