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Ligand · YCP

YCP · (2S)-piperidine-2-carboxylic acid

YCP, (2S)-piperidine-2-carboxylic acid (C6 H11 N O2, 129.2 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
YCP
Formula
C6 H11 N O2
Class
ligand
Structures
6
PDB entries
6

Binding sites

YCP in 6 structures; the first of them:

  • 5GZI · Cyclodeaminase_PA · YCP B402 · binds ARG49, GLU63, MET65, LYS77, VAL79, TYR81, ILE94, THR118 and 6 more
  • 5GZM · Cyclodeaminase_PA · YCP A402 · binds ARG49, GLU63, MET65, LYS77, VAL79, TYR81, ILE94, THR118 and 6 more
  • 5YU1 · Structural basis for recognition of L-lysine, L-ornithine, and L-2,4-diamino butyric acid… · YCP A403 · binds ARG49, GLU63, MET65, LYS77, VAL79, TYR81, ILE94, THR118 and 5 more
  • 8P2Z · Structure of human SIT1 bound to L-pipecolate (focussed map / refinement) · YCP C703 · binds TYR21, ALA22, VAL23, GLY24, LEU25, GLY26, ASN27, LEU98 and 7 more
  • 8P30 · Structure of human SIT1:ACE2 complex (open PD conformation) bound to L-pipecolate · YCP C703 · binds TYR21, ALA22, VAL23, GLY24, LEU25, GLY26, ASN27, LEU98 and 7 more
  • 8P31 · Structure of human SIT1:ACE2 complex (closed PD conformation) bound to L-pipecolate · YCP C703 · binds TYR21, ALA22, VAL23, GLY24, LEU25, GLY26, ASN27, LEU98 and 7 more
  • 8TD9 · Structure of PYCR1 complexed with NADH and L-pipecolic acid · YCP A403 · binds VAL231, SER232, SER233, GLY236, ALA237, THR238, ALA97, MET121 and 3 more

Residues it binds most

GLY 18, THR 13, SER 10, ALA 18, TYR 13, VAL 18, ARG 8, PHE 11, MET 12, ASN 5 (residue and the binding sites it lines).

Found with

  • NAD · Nicotinamide-adenine-dinucleotide
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • ZN · Zinc ion
  • BMA · beta-D-mannopyranose
  • NDG · 2-acetamido-2-deoxy-alpha-D-glucopyranose
  • CL · Chloride ion
  • NAI · 1,4-dihydronicotinamide adenine dinucleotide
  • NA · Sodium ion
  • MAN · alpha-D-mannopyranose
  • SO4 · Sulfate ion

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