Y8Y · (1R,2S)-2-((S)-2-(((((1R,3r,5S)-bicyclo[3.3.1]nonan-3-yl)methoxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-((S)-2-oxopyrrolidin-3-yl)propane-1-sulfonic acid

Binding sites

Y8Y in 4 structures; the first of them:

• 7LKR · 1.65 A resolution structure of SARS-CoV-2 3CL protease in complex with inhibitor 2a · Y8Y B401 · binds HIS41, MET49, TYR54, PHE140, LEU141, ASN142, SER144, CYS145 and 12 more
• 7LKU · 1.65 A resolution structure of SARS-CoV-2 3CL protease in complex with inhibitor 3b… · Y8Y B401 · binds HIS41, MET49, TYR54, PHE140, LEU141, ASN142, SER144, CYS145 and 12 more
• 7LKR · 1.65 a resolution structure of SARS-cov-2 3CL protease in complex with inhibitor 2A · Y8Y B401 · binds HIS41, MET49, TYR54, PHE140, LEU141, ASN142, SER144, CYS145 and 12 more
• 7LKU · 1.65 a resolution structure of SARS-cov-2 3CL protease in complex with inhibitor 3B… · Y8Y B401 · binds HIS41, MET49, TYR54, PHE140, LEU141, ASN142, SER144, CYS145 and 12 more

Residues it binds most

HIS 4, LEU 4, MET 4, ALA 4, ARG 4, ASN 4, ASP 4, CYS 4, GLN 4, GLU 4 (residue and the binding sites it lines).

Found with

• Y4D · (1R,2S)-2-((S)-2-(((((1R,3s,5S)-bicyclo[3.3.1]nonan-3-yl)methoxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-((S)-2-oxopyrrolidin-3-yl)propane-1-sulfonic acid
• Y5S · (1S,2S)-2-((S)-2-(((((1R,3s,5S)-bicyclo[3.3.1]nonan-3-yl)methoxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-((S)-2-oxopyrrolidin-3-yl)propane-1-sulfonic acid
• Y91 · (1S,2S)-2-((S)-2-(((((1R,3r,5S)-bicyclo[3.3.1]nonan-3-yl)methoxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-((S)-2-oxopyrrolidin-3-yl)propane-1-sulfonic acid
• PG4 · Tetraethylene glycol