GL1X · GenesisL1 explorer

Ligand · Y2P

Y2P · 2-[4-[(3'R,4S)-3'-fluoro-1-[2-[(4-fluorophenyl)methyl-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]amino]-2-oxo-ethyl]-2,5-dioxo-spiro[imidazolidine-4,1'-indane]-5'-yl]pyrazol-1-yl]-N-methyl-acetamide

Y2P, 2-[4-[(3'R,4S)-3'-fluoro-1-[2-[(4-fluorophenyl)methyl-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]amino]-2-oxo-ethyl]-2,5-dioxo-spiro[imidazolidine-4,1'-indane]-5'-yl]pyrazol-1-yl]-N-methyl-acetamide (C29 H27 F5 N6 O4, 618.6 g/mol), in the…

Component
Y2P
Formula
C29 H27 F5 N6 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

Y2P in 2 structures; the first of them:

  • 7LJE · Discovery of Spirohydantoins as Selective, Orally Bioavailable Inhibitors of p300/CBP… · Y2P A1701 · binds PHE1374, LEU1398, ASP1399, SER1400, TYR1414, LEU1418, PRO1440, SER1441 and 16 more
  • 7LJE · Discovery of spirohydantoins as selective, orally bioavailable inhibitors of P300/CBP… · Y2P A1701 · binds PHE1374, LEU1398, ASP1399, SER1400, TYR1414, LEU1418, PRO1440, GLU1442 and 15 more

Residues it binds most

PRO 8, ASP 8, LEU 8, TYR 8, SER 8, ARG 8, GLN 8, GLY 8, HIS 8, ILE 8 (residue and the binding sites it lines).

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