GL1X · GenesisL1 explorer

Ligand · Y2B

Y2B · 6-{[(3R,4R)-4-(2-{[(1S,2R)-2-(3-fluorophenyl)cyclopropyl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine

Y2B, 6-{[(3R,4R)-4-(2-{[(1S,2R)-2-(3-fluorophenyl)cyclopropyl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine (C22 H29 F N4 O, 384.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
Y2B
Formula
C22 H29 F N4 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

Y2B in 2 structures; the first of them:

  • 3RQJ · Structure of the neuronal nitric oxide synthase heme domain in complex with… · Y2B A800 · binds MET336, LEU337, ARG414, GLN478, PRO565, VAL567, PHE584, SER585 and 7 more
  • 3RQJ · Structure of the neuronal nitric oxide synthase heme domain in complex with… · Y2B A800 · binds MET336, LEU337, ARG414, GLN478, PRO565, VAL567, PHE584, SER585 and 7 more

Residues it binds most

TRP 4, TYR 4, ARG 4, GLN 4, GLU 4, GLY 4, LEU 4, MET 4, PHE 4, PRO 4 (residue and the binding sites it lines).

Found with

  • H4B · 5,6,7,8-tetrahydrobiopterin
  • HEM · Protoporphyrin IX containing Fe
  • ZN · Zinc ion
  • ACT · Acetate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.