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Ligand · XXZ

XXZ · 1-[4-(aminomethyl)benzoyl]-5'-fluoro-1'H-spiro[piperidine-4,2'-quinazolin]-4'-amine

XXZ, 1-[4-(aminomethyl)benzoyl]-5'-fluoro-1'H-spiro[piperidine-4,2'-quinazolin]-4'-amine (C20 H22 F N5 O, 367.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within…

Component
XXZ
Formula
C20 H22 F N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

XXZ in 2 structures; the first of them:

  • 3E65 · Murine INOS dimer with HEME, pterin and inhibitor AR-C120011 · XXZ A906 · binds GLN257, ILE259, ARG260, TYR341, PRO344, ALA345, VAL346, PHE363 and 7 more
  • 3E65 · Murine inos dimer with heme, pterin and inhibitor ar-C120011 · XXZ A906 · binds GLN257, ILE259, ARG260, TYR341, PRO344, ALA345, VAL346, PHE363 and 7 more

Residues it binds most

ARG 4, TYR 4, ALA 4, ASN 4, ASP 4, GLN 4, GLU 4, GLY 4, ILE 4, PHE 4 (residue and the binding sites it lines).

Found with

  • H4B · 5,6,7,8-tetrahydrobiopterin
  • HEM · Protoporphyrin IX containing Fe

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