Ligand · XVP
XVP · diethyl ({4-[(2S,3R)-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxy-4-({[4-(hydroxymethyl)phenyl]sulfonyl}[(2S)-2-methylbutyl]amino)butyl]phenoxy}methyl)phosphonate
XVP, diethyl ({4-[(2S,3R)-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxy-4-({[4-(hydroxymethyl)phenyl]sulfonyl}[(2S)-2-methylbutyl]amino)butyl]phenoxy}methyl)phosphonate (C34 H51 N2 O12 P S, 742.8 g/mol)…
- Component
- XVP
- Formula
- C34 H51 N2 O12 P S
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
XVP in 4 structures; the first of them:
- 7LEC · HIV-1 Protease WT (NL4-3) in Complex with PU3 (LR3-69) · XVP B101 · binds LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, ILE47 and 22 more
- 7MAG · HIV-1 Protease (I84V) in Complex with PU3 (LR3-69) · XVP A104 · binds LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, ILE47 and 23 more
- 7LEC · HIV-1 protease wt (NL4-3) in complex with PU3 (LR3-69) · XVP B101 · binds ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, ILE47, GLY48 and 17 more
- 7MAG · HIV-1 protease (I84V) in complex with PU3 (LR3-69) · XVP A104 · binds ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, ILE47, GLY48 and 16 more
Residues it binds most
GLY 4, ASP 4, ILE 4, VAL 4, LEU 4, ALA 4, PRO 4, PHE 4, ARG 2 (residue and the binding sites it lines).
Found with
- SO4 · Sulfate ion
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