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Ligand · XUV

XUV · diethyl ({4-[(2S,3R)-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl][(2S)-2-methylbutyl]amino}butyl]phenoxy}methyl)phosphonate

XUV, diethyl ({4-[(2S,3R)-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl][(2S)-2-methylbutyl]amino}butyl]phenoxy}methyl)phosphonate (C34 H51 N2 O12 P S, 742.8 g/mol), in the…

Component
XUV
Formula
C34 H51 N2 O12 P S
Class
ligand
Structures
4
PDB entries
2

Binding sites

XUV in 4 structures; the first of them:

  • 7LEB · HIV-1 Protease WT (NL4-3) in Complex with PU2 (LR2-79) · XUV A103 · binds LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, ILE47 and 22 more
  • 7MAF · HIV-1 Protease (I84V) in Complex with PU2 (LR2-79) · XUV A102 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 24 more
  • 7LEB · HIV-1 protease wt (NL4-3) in complex with PU2 (LR2-79) · XUV A103 · binds ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, ILE47, GLY48 and 16 more
  • 7MAF · HIV-1 protease (I84V) in complex with PU2 (LR2-79) · XUV A102 · binds ARG8, ASP25, GLY27, ALA28, ASP30, VAL32, ILE47, GLY48 and 16 more

Residues it binds most

GLY 4, ASP 4, ILE 4, VAL 4, ALA 4, LEU 4, PRO 4, ARG 3, PHE 4 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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