Ligand · XMV

XMV · 4-{[5-({(2S)-2-butyl-5-oxo-4-[3-(trifluoromethoxy)phenyl]piperazin-1-yl}methyl)-1H-imidazol-1-yl]methyl}benzonitrile

XMV, 4-{[5-({(2S)-2-butyl-5-oxo-4-[3-(trifluoromethoxy)phenyl]piperazin-1-yl}methyl)-1H-imidazol-1-yl]methyl}benzonitrile (C27 H28 F3 N5 O2, 511.5 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every…

Component: XMV
Formula: C27 H28 F3 N5 O2
Class: ligand
Structures: 1
PDB entries: 1

Binding sites

XMV in 1 structure; the first of them:

7T09 · Cryptococcus neoformans protein farnesyltransferase in complex with FPP and inhibitor 2d · XMV B605 · binds TYR109, LEU84, SER87, TRP90, TRP94, ARG197, ASP323, CYS325 and 5 more

Residues it binds most

TRP 1, TYR 1, ASP 1, ARG 1, CYS 1, HIS 1, LEU 1, SER 1 (residue and the binding sites it lines).

Found with

3FX · (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid
FPP · Farnesyl diphosphate
ZN · Zinc ion
EDO · 1,2-ethanediol

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