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Ligand · XIZ

XIZ · (E)-pyridin-4-yl-acrylic acid

XIZ, (E)-pyridin-4-yl-acrylic acid (C8 H7 N O2, 149.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with…

Component
XIZ
Formula
C8 H7 N O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

XIZ in 2 structures; the first of them:

  • 2XIZ · Protein kinase Pim-1 in complex with fragment-3 from crystallographic fragment screen · XIZ A1307 · binds LEU44, VAL52, ALA65, LYS67, ILE104, LEU120, GLU121, ARG122 and 3 more
  • 2XIZ · Protein kinase pim-1 in complex with fragment-3 from crystallographic fragment screen · XIZ A1307 · binds LEU44, VAL52, ALA65, LYS67, ILE104, LEU120, GLU121, ARG122 and 3 more

Residues it binds most

LEU 2, ILE 2, ALA 2, ARG 2, ASP 2, GLU 2, LYS 2, VAL 2 (residue and the binding sites it lines).

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