Ligand · XHS

XHS · 6-(2-fluoro-6-methoxyphenyl)-1-[6-(4-methylpiperazin-1-yl)pyridin-2-yl]-1H-pyrazolo[4,3-c]pyridine

XHS, 6-(2-fluoro-6-methoxyphenyl)-1-[6-(4-methylpiperazin-1-yl)pyridin-2-yl]-1H-pyrazolo[4,3-c]pyridine (C23 H23 F N6 O, 418.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component: XHS
Formula: C23 H23 F N6 O
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

XHS in 2 structures; the first of them:

7L25 · HPK1 in complex with compound 18 · XHS A301 · binds LEU23, TYR28, VAL31, ALA44, LYS46, VAL75, MET91, GLU92 and 11 more
7L25 · HPK1 in complex with compound 18 · XHS A301 · binds LEU23, TYR28, VAL31, ALA44, LYS46, MET91, GLU92, PHE93 and 7 more

Residues it binds most

ALA 4, LEU 4, GLY 4, VAL 4, ASP 4, CYS 4, GLU 4, LYS 4, MET 4, PHE 4 (residue and the binding sites it lines).

Found with

EDO · 1,2-ethanediol

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