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Ligand · XDH

XDH · 4,4'-propane-2,2-diylbis(2,6-dichlorophenol)

XDH, 4,4'-propane-2,2-diylbis(2,6-dichlorophenol) (C15 H12 Cl4 O2, 366.1 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and…

Component
XDH
Formula
C15 H12 Cl4 O2
Class
ligand
Structures
4
PDB entries
2

Binding sites

XDH in 4 structures; the first of them:

  • 3OSI · Crystal structure of PPARgamma ligand binding domain in complex with… · XDH A1 · binds LEU228, GLY284, CYS285, ARG288, SER289, ALA292, ILE326, TYR327 and 9 more
  • 4MGB · Crystal structure of hERa-LBD (Y537S) in complex with TCBPA · XDH A601 · binds LEU346, THR347, LEU349, ALA350, GLU353, TRP383, LEU384, LEU387 and 10 more
  • 3OSI · Crystal structure of ppargamma ligand binding domain in complex with… · XDH A1 · binds LEU228, GLY284, CYS285, ARG288, SER289, ALA292, ILE326, TYR327 and 9 more
  • 4MGB · Crystal structure of hera-lbd (Y537S) in complex with tcbpa · XDH A601 · binds LEU346, THR347, LEU349, ALA350, GLU353, TRP383, LEU384, LEU387 and 10 more

Residues it binds most

LEU 6, MET 6, PHE 6, ILE 6, ALA 6, ARG 6, GLU 6, GLY 6, HIS 4, SER 2 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol
  • PGO · S-1,2-propanediol

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