Ligand · XBJ
XBJ · 4-fluoro-2-(4-{[(3S,4R)-4-(1-hydroxy-1-methylethyl)pyrrolidin-3-yl]amino}-6,7-dimethoxyquinazolin-2-yl)phenol
XBJ, 4-fluoro-2-(4-{[(3S,4R)-4-(1-hydroxy-1-methylethyl)pyrrolidin-3-yl]amino}-6,7-dimethoxyquinazolin-2-yl)phenol (C23 H27 F N4 O4, 442.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (3 PDB entries). Every binding…
- Component
- XBJ
- Formula
- C23 H27 F N4 O4
- Class
- ligand
- Structures
- 4
- PDB entries
- 3
Binding sites
XBJ in 4 structures; the first of them:
- 2XBJ · Crystal Structure of Chk2 in complex with an inhibitor · XBJ A1513 · binds LEU226, GLY227, SER228, GLY229, GLY232, VAL234, ALA247, LYS249 and 14 more
- 8P5G · Kinase domain of wild type human ULK1 in complex with compound CCT241533 · XBJ A301 · binds ILE22, GLY23, HIS24, GLY25, VAL30, ALA44, LYS46, VAL76 and 12 more
- 8P5H · Kinase domain of mutant human ULK1 in complex with compound CCT241533 · XBJ A301 · binds ILE22, GLY23, HIS24, GLY25, VAL30, ALA44, LYS46, VAL76 and 12 more
- 2XBJ · Crystal structure of CHK2 in complex with an inhibitor · XBJ A1513 · binds LEU226, GLY227, SER228, GLY229, GLY232, VAL234, ALA247, LYS249 and 14 more
Residues it binds most
GLY 6, ASP 6, GLU 6, LEU 6, VAL 6, ALA 6, ASN 6, ILE 6, LYS 6, MET 6 (residue and the binding sites it lines).
Found with
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.