Ligand · X8G

X8G · 1-[(1-{2-[(3-chloro-1-methyl-1H-indazol-5-yl)amino]pyrimidin-4-yl}-3-methyl-1H-pyrazol-4-yl)methyl]azetidin-3-ol

X8G, 1-[(1-{2-[(3-chloro-1-methyl-1H-indazol-5-yl)amino]pyrimidin-4-yl}-3-methyl-1H-pyrazol-4-yl)methyl]azetidin-3-ol (C20 H21 Cl N8 O, 424.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component: X8G
Formula: C20 H21 Cl N8 O
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

X8G in 2 structures; the first of them:

4XG8 · Crystal structure of an inhibitor-bound Syk · X8G A700 · binds LEU377, GLY378, VAL385, ALA400, LYS402, GLU420, VAL433, MET448 and 11 more
4XG8 · Crystal structure of an inhibitor-bound syk · X8G A700 · binds LEU377, GLY378, VAL385, ALA400, LYS402, GLU420, VAL433, MET448 and 11 more

Residues it binds most

GLU 4, LEU 4, ALA 4, GLY 4, MET 4, VAL 4, LYS 4, ARG 4, ASN 4, ASP 4 (residue and the binding sites it lines).

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