Ligand · X5G

X5G · 1-({1-[2-({3,5-dimethyl-4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]-4-methyl-1H-pyrrol-3-yl}methyl)azetidin-3-ol

X5G, 1-({1-[2-({3,5-dimethyl-4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]-4-methyl-1H-pyrrol-3-yl}methyl)azetidin-3-ol (C27 H36 N6 O2, 476.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component: X5G
Formula: C27 H36 N6 O2
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

X5G in 2 structures; the first of them:

5GHV · Crystal structure of an inhibitor-bound Syk · X5G A701 · binds LEU377, VAL385, ALA400, LYS402, GLU420, VAL433, MET448, GLU449 and 11 more
5GHV · Crystal structure of an inhibitor-bound syk · X5G A701 · binds LEU377, VAL385, ALA400, LYS402, GLU420, VAL433, MET448, GLU449 and 11 more

Residues it binds most

GLU 4, LEU 4, ALA 4, MET 4, VAL 4, LYS 4, ARG 4, ASN 4, ASP 4, GLY 4 (residue and the binding sites it lines).

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