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Ligand · X2M

X2M · (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one

X2M, (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one (C15 H14 N2 O, 238.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
X2M
Formula
C15 H14 N2 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

X2M in 2 structures; the first of them:

  • 2X2M · Crystal Structure of phosphorylated RET tyrosine kinase domain with inhibitor · X2M A2016 · binds LEU730, VAL738, ALA756, LYS758, ILE788, VAL804, GLU805, TYR806 and 6 more
  • 2X2M · Crystal structure of phosphorylated ret tyrosine kinase domain with inhibitor · X2M A2016 · binds LEU730, VAL738, ALA756, LYS758, ILE788, VAL804, GLU805, TYR806 and 6 more

Residues it binds most

ALA 4, LEU 4, LYS 4, SER 4, VAL 4, GLU 4, GLY 4, ILE 4, TYR 4, ASP 2 (residue and the binding sites it lines).

Found with

  • FMT · Formic acid

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