X2A · (6S,8R)-N,N'-bis[3-({4-[3-(aminomethyl)phenyl]piperidin-1-yl}carbonyl)phenyl]-8-hydroxy-6-(1-hydroxycyclobutyl)-5,7-dioxaspiro[3.4]octane-6,8-dicarboxamide

Binding sites

X2A in 2 structures; the first of them:

• 4MPU · Human beta-tryptase co-crystal structure with (6S,8R)-N,N'-bis[3-({4-[3-(aminomethyl)pheny… · X2A B301 · binds TYR114, THR115, GLN117, ASP218, SER219, CYS220, GLN221, SER224 and 22 more
• 4MPU · Human beta-tryptase co-crystal structure with (6S,8R)-N,N'-BIS[3-({4… · X2A B301 · binds TYR114, THR115, GLN117, ASP218, SER219, CYS220, GLN221, SER224 and 22 more

Residues it binds most

GLY 2, CYS 2, GLN 2, SER 2, ASP 2, GLU 2, THR 2, TRP 2, TYR 2, VAL 2 (residue and the binding sites it lines).

Found with

• SO4 · Sulfate ion
• MES · 2-(N-morpholino)-ethanesulfonic acid
• PG4 · Tetraethylene glycol