Ligand · WZV
WZV · 5-(2,2,2-Trifluoro-ethoxy)-pyridine-2-carboxylic acid [3-((S)-2-amino-1,4-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-4-yl)-phenyl]-amide
WZV, 5-(2,2,2-Trifluoro-ethoxy)-pyridine-2-carboxylic acid [3-((S)-2-amino-1,4-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-4-yl)-phenyl]-amide (C20 H20 F3 N5 O3, 435.4 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4…
- Component
- WZV
- Formula
- C20 H20 F3 N5 O3
- Class
- ligand
- Structures
- 8
- PDB entries
- 4
Binding sites
WZV in 8 structures; the first of them:
- 3ZKI · BACE2 mutant structure with ligand · WZV A1398 · binds GLY27, ARG28, GLY29, TYR30, LEU46, ASP48, GLY50, SER51 and 12 more
- 3ZKN · BACE2 Fab inhibitor complex · WZV A1398 · binds LEU46, ASP48, GLY50, SER51, TYR87, GLN89, ASN123, PHE124 and 6 more
- 3ZKS · BACE2 xaperone complex with inhibitor · WZV A1398 · binds GLY29, TYR30, LEU46, ASP48, GLY50, SER51, TYR87, PHE124 and 10 more
- 3ZOV · Crystal structure of bace-1 in complex with chemical ligand · WZV A1447 · binds SER71, GLY72, GLN73, GLY74, TYR75, LEU91, ASP93, GLY95 and 13 more
- 3ZKI · BACE2 mutant structure with ligand · WZV A1398 · binds GLY27, ARG28, GLY29, TYR30, LEU46, ASP48, GLY50, SER51 and 12 more
- 3ZKN · BACE2 Fab inhibitor complex · WZV A1398 · binds LEU46, ASP48, GLY50, SER51, TYR87, GLN89, ASN123, PHE124 and 6 more
- 3ZKS · BACE2 xaperone complex with inhibitor · WZV A1398 · binds GLY29, TYR30, LEU46, ASP48, GLY50, SER51, TYR87, PHE124 and 10 more
- 3ZOV · Crystal structure of bace-1 in complex with chemical ligand · WZV A1447 · binds SER71, GLY72, GLN73, GLY74, TYR75, LEU91, ASP93, GLY95 and 13 more
Residues it binds most
GLY 12, ASP 12, THR 12, SER 12, TYR 12, LEU 12, ILE 12, PHE 12, TRP 12, ALA 8 (residue and the binding sites it lines).
Found with
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.