GL1X · GenesisL1 explorer

Ligand · WZG

WZG · [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R)-3-hydroxy-2,2-dimethyl-4-[(3-{[2-(methylsulfanyl) ethyl]amino}-3-oxopropyl)amino]-4-oxobutyl dihydrogen diphosphate (non-preferred name)

WZG, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R)-3-hydroxy-2,2-dimethyl-4-[(3-{[2-(methylsulfanyl) ethyl]amino}-3-oxopropyl)amino]-4-oxobutyl dihydrogen diphosphate (non-preferred…

Component
WZG
Formula
C22 H38 N7 O16 P3 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

WZG in 2 structures; the first of them:

  • 7KPU · Crystal structure of human NatD (NAA40) bound to a bisubstrate analogue with a C-3 linker · WZG E301 · binds ASN80, MET81, MET84, VAL140, GLN141, LEU142, ARG147, ARG148 and 16 more
  • 7KPU · Crystal structure of human natd (NAA40) bound to a bisubstrate analogue with a C-3 linker · WZG E301 · binds ASN80, MET81, MET84, VAL140, GLN141, LEU142, ARG147, ARG148 and 16 more

Residues it binds most

GLY 4, LEU 4, ALA 4, ARG 4, ASN 4, GLN 4, LYS 4, PHE 4, VAL 4, MET 4 (residue and the binding sites it lines).

Found with

  • ACE · Acetyl group
  • NH2 · Amino group
  • SO4 · Sulfate ion
  • BTB · 2-[bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol
  • GOL · Glycerol

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