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Ligand · WXV

WXV · N,1-dimethyl-8-{[1-(methylsulfonyl)piperidin-4-yl]amino}-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide

WXV, N,1-dimethyl-8-{[1-(methylsulfonyl)piperidin-4-yl]amino}-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (C18 H23 N7 O3 S, 417.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
WXV
Formula
C18 H23 N7 O3 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

WXV in 2 structures; the first of them:

  • 2WXV · Structure of CDK2-CYCLIN A with a Pyrazolo(4,3-h) quinazoline-3- carboxamide inhibitor · WXV A1299 · binds ILE10, GLY11, TYR15, VAL18, ALA31, LYS33, GLU51, VAL64 and 10 more
  • 2WXV · Structure of CDK2-cyclin a with a PYRAZOLO(4,3-H) quinazoline-3- carboxamide inhibitor · WXV A1299 · binds ILE10, GLY11, TYR15, VAL18, ALA31, LYS33, GLU51, VAL64 and 10 more

Residues it binds most

ASP 4, GLU 4, LEU 4, LYS 4, PHE 4, VAL 4, ALA 4, GLN 4, GLY 4, HIS 4 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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