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Ligand · WI2

WI2 · 1-[3-amino-6-(3-methoxyphenyl)pyrazin-2-yl]piperidine-4-carboxylic acid

WI2, 1-[3-amino-6-(3-methoxyphenyl)pyrazin-2-yl]piperidine-4-carboxylic acid (C17 H20 N4 O3, 328.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
WI2
Formula
C17 H20 N4 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

WI2 in 2 structures; the first of them:

  • 2XKE · Structure of Nek2 bound to Aminipyrazine Compound 5 · WI2 A1280 · binds ILE14, CYS22, VAL35, LYS37, VAL68, TYR70, MET86, GLU87 and 7 more
  • 2XKE · Structure of NEK2 bound to aminipyrazine compound 5 · WI2 A1280 · binds ILE14, CYS22, VAL35, LYS37, VAL68, TYR70, MET86, GLU87 and 7 more

Residues it binds most

ASP 2, CYS 2, GLY 2, TYR 2, VAL 2, GLU 2, ILE 2, LYS 2, MET 2, PHE 2 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion

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