GL1X · GenesisL1 explorer

Ligand · WFV

WFV · (1S,2R,3aR,4S,6aR)-4-[(2-amino-3,5-difluoroquinolin-7-yl)methyl]-2-(4-amino-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)hexahydropentalene-1,6a(1H)-diol

WFV, (1S,2R,3aR,4S,6aR)-4-[(2-amino-3,5-difluoroquinolin-7-yl)methyl]-2-(4-amino-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)hexahydropentalene-1,6a(1H)-diol (C24 H23 F3 N6 O2, 484.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2…

Component
WFV
Formula
C24 H23 F3 N6 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

WFV in 2 structures; the first of them:

  • 7KID · PRMT5:MEP50 Complexed with 5,5-Bicyclic Inhibitor Compound 72 · WFV A705 · binds LEU312, PRO314, LEU315, LEU319, TYR324, PHE327, LYS333, TYR334 and 17 more
  • 7KID · PRMT5:MEP50 complexed with 5,5-bicyclic inhibitor compound 72 · WFV A705 · binds LEU312, PRO314, LEU315, LEU319, TYR324, PHE327, LYS333, TYR334 and 17 more

Residues it binds most

LEU 2, GLU 2, GLY 2, LYS 2, SER 2, TYR 2, ARG 2, ASN 2, ASP 2, CYS 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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