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Ligand · WFG

WFG · 6-[(2S)-4-(4-fluorophenyl)-2-methyl-5-oxo-2,5-dihydrofuran-3-yl]-2H-1,4-benzoxazin-3(4H)-one

WFG, 6-[(2S)-4-(4-fluorophenyl)-2-methyl-5-oxo-2,5-dihydrofuran-3-yl]-2H-1,4-benzoxazin-3(4H)-one (C19 H14 F N O4, 339.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
WFG
Formula
C19 H14 F N O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

WFG in 2 structures; the first of them:

  • 3WFG · Mineralocorticoid receptor ligand-binding domain with compuond 2e · WFG A1001 · binds LEU766, LEU769, ASN770, ALA773, TRP806, MET807, LEU810, SER811 and 12 more
  • 3WFG · Mineralocorticoid receptor ligand-binding domain with compuond 2E · WFG A1001 · binds LEU766, LEU769, ASN770, ALA773, TRP806, MET807, LEU810, SER811 and 12 more

Residues it binds most

LEU 2, MET 2, PHE 2, CYS 2, ALA 2, ASN 2, SER 2, THR 2, TRP 2, VAL 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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