Ligand · WFD
WFD · 1-[4-(4-{4-(4-methylpiperazin-1-yl)-6-[(3-methyl-1H-pyrazol-5-yl)amino]pyrimidin-2-yl}phenyl)piperidin-1-yl]prop-2-en-1-one
WFD, 1-[4-(4-{4-(4-methylpiperazin-1-yl)-6-[(3-methyl-1H-pyrazol-5-yl)amino]pyrimidin-2-yl}phenyl)piperidin-1-yl]prop-2-en-1-one (C27 H34 N8 O, 486.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…
- Component
- WFD
- Formula
- C27 H34 N8 O
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
WFD in 2 structures; the first of them:
- 7KIA · Crystal structure of FGFR2 kinase domain gatekeeper mutant V564F in complex with covalent… · WFD A801 · binds LEU487, GLY488, GLU489, GLY490, CYS491, PHE492, VAL495, ALA515 and 12 more
- 7KIA · Crystal structure of FGFR2 kinase domain gatekeeper mutant V564F in complex with covalent… · WFD A801 · binds LEU487, GLY488, GLU489, GLY490, CYS491, PHE492, VAL495, ALA515 and 9 more
Residues it binds most
GLY 4, ALA 4, GLU 4, LEU 4, PHE 4, LYS 4, ASP 4, CYS 4, SER 4, TYR 4 (residue and the binding sites it lines).
Found with
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