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Ligand · WBM

WBM · 2,3-diphenyl-5-[(1H-pyrazol-3-yl)amino]pyrazolo[1,5-a]pyrimidin-7(4H)-one

WBM, 2,3-diphenyl-5-[(1H-pyrazol-3-yl)amino]pyrazolo[1,5-a]pyrimidin-7(4H)-one (C21 H16 N6 O, 368.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
WBM
Formula
C21 H16 N6 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

WBM in 2 structures; the first of them:

  • 7KDA · Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with SAM… · WBM A505 · binds GLY16, THR17, PHE18, LEU19, PHE20, GLN190, GLY193, GLY273 and 3 more
  • 7KDA · Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with SAM… · WBM A505 · binds GLY16, THR17, PHE18, LEU19, PHE20, GLN190, GLY193, GLY273 and 3 more

Residues it binds most

GLY 2, PHE 2, ARG 2, GLN 2, LEU 2, THR 2, TRP 2 (residue and the binding sites it lines).

Found with

  • SAM · S-adenosylmethionine
  • CL · Chloride ion
  • GOL · Glycerol
  • TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol

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