GL1X · GenesisL1 explorer

Ligand · W6U

W6U · (2S,4R)-1-[(2S)-3,3-dimethyl-2-[3-[4-[4-[4-[[3-oxidanylidene-1-[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]-2-prop-2-enyl-pyrazolo[3,4-d]pyrimidin-6-yl]amino]phenyl]piperazin-1-yl]butoxy]propanoylamino]butanoyl]-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide

W6U, (2S,4R)-1-[(2S)-3,3-dimethyl-2-[3-[4-[4-[4-[[3-oxidanylidene-1-[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]-2-prop-2-enyl-pyrazolo[3,4-d]pyrimidin-6-yl]amino]phenyl]piperazin-1-yl]butoxy]propanoylamino]butanoyl]-N-[[4-(4-methyl-1,3-thiazol…

Component
W6U
Formula
C55 H70 N12 O7 S
Class
ligand
Structures
1
PDB entries
1

Binding sites

W6U in 1 structure; the first of them:

  • 8WDK · The complex structure of Cul2-VCB-Protac-Wee1 · W6U V301 · binds ARG69, TRP88, PHE91, TYR98, PRO99, LEU101, ARG107, ILE109 and 23 more

Residues it binds most

ASN 1, GLY 1, PHE 1, SER 1, TYR 1, ARG 1, HIS 1, ILE 1, TRP 1, ALA 1 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.