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Ligand · W2K

W2K · 4-(4-Methylpiperazin-1-yl)-N-(2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin-3-yl)benzamide

W2K, 4-(4-Methylpiperazin-1-yl)-N-(2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin-3-yl)benzamide (C22 H23 N5 O2, 389.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within…

Component
W2K
Formula
C22 H23 N5 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

W2K in 2 structures; the first of them:

  • 4CV9 · MPS1 kinase with 3-aminopyridin-2-one inhibitors · W2K A1795 · binds ILE531, VAL539, ALA551, LYS553, ILE586, MET602, GLU603, CYS604 and 7 more
  • 4CV9 · MPS1 kinase with 3-aminopyridin-2-one inhibitors · W2K A1795 · binds ILE531, VAL539, ALA551, LYS553, ILE586, MET602, GLU603, CYS604 and 7 more

Residues it binds most

ILE 2, ALA 2, ASN 2, ASP 2, CYS 2, GLU 2, GLY 2, LEU 2, LYS 2, MET 2 (residue and the binding sites it lines).

Found with

  • DMS · Dimethyl sulfoxide
  • EDO · 1,2-ethanediol

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