GL1X · GenesisL1 explorer

Ligand · VYG

VYG · 6-ethyl-5-[3-({3-[4-(trifluoromethyl)piperidin-1-yl]pyridin-2-yl}oxy)propoxy]pyrimidine-2,4-diamine

VYG, 6-ethyl-5-[3-({3-[4-(trifluoromethyl)piperidin-1-yl]pyridin-2-yl}oxy)propoxy]pyrimidine-2,4-diamine (C20 H27 F3 N6 O2, 440.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
VYG
Formula
C20 H27 F3 N6 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

VYG in 2 structures; the first of them:

  • 7K6A · Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in… · VYG A202 · binds ILE7, TRP8, ALA9, ILE22, ASP29, LEU30, PHE33, LYS34 and 10 more
  • 7K6A · Crystal structure of dihydrofolate reductase (DHFR) from mycobacterium ulcerans AGY99 in… · VYG A202 · binds ILE7, TRP8, ALA9, ILE22, ASP29, LEU30, PHE33, LYS34 and 9 more

Residues it binds most

ILE 2, LEU 2, PRO 2, THR 2, ALA 2, ARG 2, ASP 2, HIS 2, LYS 2, PHE 2 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
  • CL · Chloride ion
  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.