Ligand · VYE

VYE · (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-N-(3-methylbutyl)piperidine-3-carboxamide

VYE, (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-N-(3-methylbutyl)piperidine-3-carboxamide (C23 H35 Cl N4 O2, 435.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component: VYE
Formula: C23 H35 Cl N4 O2
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

VYE in 2 structures; the first of them:

3VYE · Human renin in complex with inhibitor 7 · VYE A402 · binds GLN19, VAL36, ASP38, GLY40, SER41, ARG82, TYR83, SER84 and 12 more
3VYE · Human renin in complex with inhibitor 7 · VYE A402 · binds GLN19, VAL36, ASP38, GLY40, SER41, ARG82, TYR83, SER84 and 12 more

Residues it binds most

SER 4, ALA 4, ASP 4, GLN 4, GLY 4, PHE 4, VAL 4, THR 4, ARG 4, ILE 4 (residue and the binding sites it lines).

Found with

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose

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