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Ligand · VXR

VXR · (5Z)-5-[(5-ethyl-2-furyl)methylene]-2-{[(S)-(4-fluorophenyl)(1h-tetrazol-5-yl)methyl]amino}-1,3-thiazol-4(5H)-one

VXR, (5Z)-5-[(5-ethyl-2-furyl)methylene]-2-{[(S)-(4-fluorophenyl)(1h-tetrazol-5-yl)methyl]amino}-1,3-thiazol-4(5H)-one (C18 H15 F N6 O2 S, 398.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
VXR
Formula
C18 H15 F N6 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

VXR in 2 structures; the first of them:

  • 2I1R · Novel Thiazolones as HCV NS5B Polymerase Inhibitors: Further Designs, Synthesis, SAR and… · VXR A600 · binds LEU419, ARG422, MET423, LEU474, HIS475, SER476, TYR477, ILE482 and 7 more
  • 2I1R · Novel thiazolones as HCV NS5B polymerase inhibitors: further designs, synthesis, sar and… · VXR A600 · binds LEU419, ARG422, MET423, LEU474, HIS475, SER476, TYR477, ILE482 and 7 more

Residues it binds most

LEU 4, ARG 4, ALA 4, HIS 4, ILE 4, LYS 4, MET 4, SER 4, TRP 4, TYR 4 (residue and the binding sites it lines).

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